Risk Management of Ceftiofur for Livestock Animals
The results of risk assessment of ceftiofur used for cattle and swine in the approval and reexamination by the Food Safety Commission of Japan, showed that the risk for antimicrobial resistance of Salmonella and Escherichia coli is evaluated to be medium and low level respectively. Now, we would like to report that the Ministry of Agriculture, Forestry and Fisheries formulated risk management measures based on the results of risk assessments.
Ceftiofur, the first third-generation cephalosporin preparation to be approved, has concerns about the selection of antimicrobial resistant bacteria and its effect on human health. Therefore, the judicious use of ceftiofur is further required, as well as cefquinome which is also a third-generation cephalosporin, fluoroquinolone, tulathromycin: 15-membered macrolide, and colistin sulfate: polymyxin family.